Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling

The IFN-inducible immunity-related p47 GTPase Irgm1 has been linked to Crohn disease as well as susceptibility to tuberculosis. Previously we demonstrated that HSC quiescence and function are aberrant in mice lacking Irgm1. To investigate the molecular basis for these defects, we conducted microarra...

詳細記述

保存先:
書誌詳細
主要な著者: King, Katherine Y., Baldridge, Megan T., Weksberg, David C., Chambers, Stuart M., Lukov, Georgi L., Wu, Shihua, Boles, Nathan C., Jung, Sung Yun, Qin, Jun, Liu, Dan, Songyang, Zhou, Eissa, N. Tony, Taylor, Gregory A., Goodell, Margaret A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2011
主題:
Hematopoiesis and Stem Cells
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156044/
https://ncbi.nlm.nih.gov/pubmed/21633090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-328682
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