Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling

The IFN-inducible immunity-related p47 GTPase Irgm1 has been linked to Crohn disease as well as susceptibility to tuberculosis. Previously we demonstrated that HSC quiescence and function are aberrant in mice lacking Irgm1. To investigate the molecular basis for these defects, we conducted microarra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: King, Katherine Y., Baldridge, Megan T., Weksberg, David C., Chambers, Stuart M., Lukov, Georgi L., Wu, Shihua, Boles, Nathan C., Jung, Sung Yun, Qin, Jun, Liu, Dan, Songyang, Zhou, Eissa, N. Tony, Taylor, Gregory A., Goodell, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156044/
https://ncbi.nlm.nih.gov/pubmed/21633090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-328682
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados