Phenserine regulates translation of β-amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development

The reduction in levels of the potentially toxic amyloid-β peptide (Aβ) has emerged as one of the most important therapeutic goals in Alzheimer's disease. Key targets for this goal are factors that affect the expression and processing of the Aβ precursor protein (βAPP). Earlier reports from our...

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Detalhes bibliográficos
Main Authors: Shaw, Karen T. Y., Utsuki, Tadanobu, Rogers, Jack, Yu, Qian-Sheng, Sambamurti, Kumar, Brossi, Arnold, Ge, Yuan-Wen, Lahiri, Debomoy K., Greig, Nigel H.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34715/
https://ncbi.nlm.nih.gov/pubmed/11404470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131152998
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