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Centrosome Aberrations Associated with Cellular Senescence and p53 Localization at Supernumerary Centrosomes

Centrosome overduplication or amplification has been observed in many human cancers and in premalignant tissue, but the mechanisms leading to such centrosome aberrations are not fully understood. We previously showed that abnormal mitotic cells with supernumerary centrosomes increase with replicativ...

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Detalhes bibliográficos
Autor principal: Ohshima, Susumu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471474/
https://ncbi.nlm.nih.gov/pubmed/23091651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/217594
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