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Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

As DNA sequencing technology has markedly advanced in recent years(2), it has become increasingly evident that the amount of genetic variation between any two individuals is greater than previously thought(3). In contrast, array-based genotyping has failed to identify a significant contribution of c...

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Bibliographic Details
Main Authors: Vallania, Francesco, Ramos, Enrique, Cresci, Sharon, Mitra, Robi D., Druley, Todd E.
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471313/
https://ncbi.nlm.nih.gov/pubmed/22760212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3943
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