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Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Conventional next-generation sequencing techniques (NGS) have allowed for immense genomic characterization for over a decade. Specifically, NGS has been used to analyze the spectrum of clonal mutations in malignancy. Though far more efficient than traditional Sanger methods, NGS struggles with ident...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Wong, Wing H., Tong, R. Spencer, Young, Andrew L., Druley, Todd E.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126605/
https://ncbi.nlm.nih.gov/pubmed/30124656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57509
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