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Isolation of Ribosome Bound Nascent Polypeptides in vitro to Identify Translational Pause Sites Along mRNA

The rate of translational elongation is non-uniform. mRNA secondary structure, codon usage and mRNA associated proteins may alter ribosome movement on the message(for review see 1). However, it's now widely accepted that synonymous codon usage is the primary cause of non-uniform translational e...

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Detalhes bibliográficos
Main Authors: Jha, Sujata S., Komar, Anton A.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471273/
https://ncbi.nlm.nih.gov/pubmed/22806127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4026
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