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Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin
BACKGROUND: Mammalian cells employ at least two subpathways of non-homologous end-joining for the repair of ionizing radiation induced DNA double strand breaks: The canonical DNA-PK-dependent form of non-homologous end-joining (D-NHEJ) and an alternative, slowly operating, error-prone backup pathway...
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Главные авторы: | , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
BioMed Central
2012
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Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471266/ https://ncbi.nlm.nih.gov/pubmed/22908892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-3-4 |
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