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Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector
Adaptive immunity depends on lymphocyte adhesion that is mediated by the integrin lymphocyte functional antigen 1 (LFA-1). The small guanosine triphosphatase Rap1 regulates LFA-1 adhesiveness through one of its effectors, Rap1-interacting adapter molecule (RIAM). We show that RIAM was recruited to t...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471229/ https://ncbi.nlm.nih.gov/pubmed/23045549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201201157 |
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