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More than insulator: multiple roles of CTCF at the H19-Igf2 imprinted domain
CTCF (CCCTC-binding factor)-mediated insulation at the H19-Insulin-like growth factor 2 (Igf2) imprinted domain is a classic example for imprinted gene regulation. DNA methylation difference in the imprinting control region (ICR) is inherited from the gametes and subsequently determines parental all...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471092/ https://ncbi.nlm.nih.gov/pubmed/23087708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00214 |
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