CTCF-Dependent Chromatin Bias Constitutes Transient Epigenetic Memory of the Mother at the H19-Igf2 Imprinting Control Region in Prospermatogonia

Genomic imprints—parental allele-specific DNA methylation marks at the differentially methylated regions (DMRs) of imprinted genes—are erased and reestablished in germ cells according to the individual's sex. Imprint establishment at paternally methylated germ line DMRs occurs in fetal male ger...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Dong-Hoon, Singh, Purnima, Tsai, Shirley Y., Oates, Nathan, Spalla, Alexander, Spalla, Claudio, Brown, Lucy, Rivas, Guillermo, Larson, Garrett, Rauch, Tibor A., Pfeifer, Gerd P., Szabó, Piroska E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991272/
https://ncbi.nlm.nih.gov/pubmed/21124827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001224
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