CTCF-Dependent Chromatin Bias Constitutes Transient Epigenetic Memory of the Mother at the H19-Igf2 Imprinting Control Region in Prospermatogonia

Genomic imprints—parental allele-specific DNA methylation marks at the differentially methylated regions (DMRs) of imprinted genes—are erased and reestablished in germ cells according to the individual's sex. Imprint establishment at paternally methylated germ line DMRs occurs in fetal male ger...

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Detalhes bibliográficos
Main Authors: Lee, Dong-Hoon, Singh, Purnima, Tsai, Shirley Y., Oates, Nathan, Spalla, Alexander, Spalla, Claudio, Brown, Lucy, Rivas, Guillermo, Larson, Garrett, Rauch, Tibor A., Pfeifer, Gerd P., Szabó, Piroska E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991272/
https://ncbi.nlm.nih.gov/pubmed/21124827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001224
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