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NF-kappaB activation: Tax sumoylation is out, but what about Tax ubiquitination?

Activation of the NF-κB transcription factors by the viral protein Tax plays a vital role in the pathogenesis of diseases associated with human T-cell lymphotropic virus type I (HTLV-I). The Tax oncoprotein undergoes constitutive K63-linked ubiquitination and sumoylation; however, the roles and mole...

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Hlavní autor: Xiao, Gutian
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470980/
https://ncbi.nlm.nih.gov/pubmed/23009565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-78
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