Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation

BACKGROUND: The Tax protein encoded by Human T-lymphotropic virus type 1 (HTLV-1) is a powerful activator of the NF-κB pathway, a property critical for HTLV-1-induced immortalization of CD4(+) T lymphocytes. Tax permanently stimulates this pathway at a cytoplasmic level by activating the IκB kinase...

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Hlavní autoři: Bonnet, Amandine, Randrianarison-Huetz, Voahangy, Nzounza, Patrycja, Nedelec, Martine, Chazal, Maxime, Waast, Laetitia, Pene, Sabrina, Bazarbachi, Ali, Mahieux, Renaud, Bénit, Laurence, Pique, Claudine
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476979/
https://ncbi.nlm.nih.gov/pubmed/23009398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-77
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