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A Non-SUMOylated Tax Protein Is Still Functional for NF-κB Pathway Activation

Whether NF-κB promoter transactivation by the human T-cell leukemia virus type 1 (HTLV-1) Tax protein requires Tax SUMOylation is still a matter of debate. In this study, we revisited the role of Tax SUMOylation using a strategy based on the targeting of Ubc9, the unique E2 SUMO-conjugating enzyme....

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Detalhes bibliográficos
Main Authors: Pène, Sabrina, Waast, Laetitia, Bonnet, Amandine, Bénit, Laurence, Pique, Claudine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178874/
https://ncbi.nlm.nih.gov/pubmed/24991007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01827-14
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