RNase H2-Initiated Ribonucleotide Excision Repair

Ribonucleotides are incorporated into DNA by the replicative DNA polymerases at frequencies of about 2 per kb which makes them by far the most abundant form of potential DNA damage in the cell. Their removal is essential for restoring a stable intact chromosome. Here we present a complete biochemica...

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Main Authors: Sparks, Justin L., Chon, Hyongi, Cerritelli, Susana M., Kunkel, Thomas A., Johansson, Erik, Crouch, Robert J., Burgers, Peter M.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470915/
https://ncbi.nlm.nih.gov/pubmed/22864116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.06.035
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