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Bleomycin in Octaarginine-modified Fusogenic Liposomes Results in Improved Tumor Growth Inhibition

Bleomycin (BLM) is an example of an anticancer drug that should be delivered into cytosol for its efficient therapeutic action. With this in mind, we developed octaarginine (R8)-modified fusogenic DOPE-liposomes (R8-DOPE-BLM). R8-modification dramatically increased (up to 50-fold) the cell-liposome...

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Bibliografische gegevens
Hoofdauteurs: Koshkaryev, Alexander, Piroyan, Aleksandr, Torchilin, Vladimir P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470833/
https://ncbi.nlm.nih.gov/pubmed/22743614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.06.008
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