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Bleomycin in Octaarginine-modified Fusogenic Liposomes Results in Improved Tumor Growth Inhibition

Bleomycin (BLM) is an example of an anticancer drug that should be delivered into cytosol for its efficient therapeutic action. With this in mind, we developed octaarginine (R8)-modified fusogenic DOPE-liposomes (R8-DOPE-BLM). R8-modification dramatically increased (up to 50-fold) the cell-liposome...

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Hlavní autoři: Koshkaryev, Alexander, Piroyan, Aleksandr, Torchilin, Vladimir P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470833/
https://ncbi.nlm.nih.gov/pubmed/22743614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.06.008
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