Ischemic Preconditioning Preserves Mitochondrial Membrane Potential and Limits Reactive Oxygen Species Production

BACKGROUND: Mitochondrial superoxide radical (O(2)(•−)) production increases after cardiac ischemia-reperfusion (IR). Ischemic preconditioning (IPC) preserves mitochondrial function and attenuates O(2)(•−) production, but the mechanism is unknown. Mitochondrial membrane potential (mΔΨ) is known to a...

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Main Authors: Quarrie, Ricardo, Lee, Daniel S., Steinbaugh, Gregory, Cramer, Brandon, Erdahl, Warren, Pfeiffer, Douglas R., Zweier, Jay L., Crestanello, Juan A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470827/
https://ncbi.nlm.nih.gov/pubmed/22763215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2012.05.090
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