Priming of reovirus transcription by GppppG and formation of CpG(5')GpC.
Compounds of general structure N(5')pn(5')N were used by the reovirus-associated RNA polymerase as primers for template-directed synthesis of virus-specific oligonucleotides and RNA. Structural requirements for activity included a guanosine residue and at least four phosphates--i.e., G(5')pppp(5')N....
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1982
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347075/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6959105/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.20.6142 |
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