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Proximity of the substrate binding site and the heme-iron catalytic site in cytochrome P-450scc.

As an approach to "mapping" the active site of the cytochrome P-450 that catalyzes cholesterol side-chain cleavage, designated cytochrome P-450scc, we have synthesized steroid derivatives with the potential to interact with both the substrate binding site and the heme-iron catalytic site o...

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Detalles Bibliográficos
Main Authors: Sheets, J J, Vickery, L E
Formato: Artigo
Idioma:Inglês
Publicado: 1982
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC346992/
https://ncbi.nlm.nih.gov/pubmed/6964388
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