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The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b
CDK9, the kinase of positive transcription elongation factor b (P-TEFb), stimulates transcription elongation by phosphorylating RNA polymerase II and transcription elongation factors. Using kinetic analysis of a human P-TEFb complex consisting of CDK9 and cyclin T, we show that the CDK9 C-terminal t...
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Huvudupphovsmän: | , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
Cell Press
2012
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3469819/ https://ncbi.nlm.nih.gov/pubmed/22959624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.011 |
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