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Validation of a novel secretion modification region (SMR) of HIV-1 Nef using cohort sequence analysis and molecular modeling

The HIV-1 accessory protein Nef plays an active role in the pathogenesis of AIDS by its numerous cellular interactions that facilitate the release of virus particles. This 27 kDa protein is required for maintenance of the viral replication in HIV, and is also known to contribute to immune evasion, b...

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Autors principals: Campbell, Patrick E., Isayev, Olexandr, Ali, Syed A., Roth, William W., Huang, Ming-Bo, Powell, Michael D., Leszczynski, Jerzy, Bond, Vincent C.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469780/
https://ncbi.nlm.nih.gov/pubmed/22643973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-012-1452-x
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