Hepatocyte specific deletion of farnesoid X receptor delays, but does not inhibit liver regeneration after partial hepatectomy in mice

Farnesoid X Receptor (FXR), the primary bile acid-sensing nuclear receptor, also plays a role in stimulation of liver regeneration. Whole body deletion of FXR results in significant inhibition of liver regeneration after partial hepatectomy (PHX). FXR is expressed in liver and intestine and recent C...

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Autori principali: Borude, Prachi, Edwards, Genea, Walesky, Chad, Li, Feng, Ma, Xiaochao, Kong, Bo, Guo, Grace L., Apte, Udayan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469721/
https://ncbi.nlm.nih.gov/pubmed/22730081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25918
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