Loss of MLK3 signaling impedes ulcer healing by modulating MAPK signaling in mouse intestinal mucosa

Mixed-lineage kinase 3 (MLK3) activates multiple MAPK pathways and can initiate apoptosis, proliferation, migration, or differentiation in different cell types. However, whether MLK3 signaling regulates intestinal epithelial cell sheet migration in vivo is not known. We sought to investigate whether...

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Main Authors: Kovalenko, Pavlo L., Kunovska, Lyudmyla, Chen, Jian, Gallo, Kathleen A., Basson, Marc D.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2012
主題:
Mucosal Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469692/
https://ncbi.nlm.nih.gov/pubmed/22917630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00158.2012
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