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Loss of MLK3 signaling impedes ulcer healing by modulating MAPK signaling in mouse intestinal mucosa

Mixed-lineage kinase 3 (MLK3) activates multiple MAPK pathways and can initiate apoptosis, proliferation, migration, or differentiation in different cell types. However, whether MLK3 signaling regulates intestinal epithelial cell sheet migration in vivo is not known. We sought to investigate whether...

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Detalhes bibliográficos
Main Authors: Kovalenko, Pavlo L., Kunovska, Lyudmyla, Chen, Jian, Gallo, Kathleen A., Basson, Marc D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469692/
https://ncbi.nlm.nih.gov/pubmed/22917630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00158.2012
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