Loss of MLK3 signaling impedes ulcer healing by modulating MAPK signaling in mouse intestinal mucosa

Mixed-lineage kinase 3 (MLK3) activates multiple MAPK pathways and can initiate apoptosis, proliferation, migration, or differentiation in different cell types. However, whether MLK3 signaling regulates intestinal epithelial cell sheet migration in vivo is not known. We sought to investigate whether...

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Autori principali: Kovalenko, Pavlo L., Kunovska, Lyudmyla, Chen, Jian, Gallo, Kathleen A., Basson, Marc D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
Soggetti:
Mucosal Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469692/
https://ncbi.nlm.nih.gov/pubmed/22917630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00158.2012
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