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Interleukin-11 protects against renal ischemia and reperfusion injury

Renal ischemia reperfusion (IR) injury causes renal tubular necrosis, apoptosis, and inflammation leading to acute and chronic kidney dysfunction. IL-11 is a multifunctional hematopoietic cytokine clinically approved to treat chemotherapy-induced thrombocytopenia. Recent studies suggest that IL-11 a...

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Autori principali: Lee, H. Thomas, Park, Sang Won, Kim, Mihwa, Ham, Ahrom, Anderson, Lana J., Brown, Kevin M., D'Agati, Vivette D., Cox, George N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469680/
https://ncbi.nlm.nih.gov/pubmed/22859402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00220.2012
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