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Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles

GLUT4-containing vesicles cycle between the plasma membrane and intracellular compartments. Insulin promotes GLUT4 exocytosis by regulating GLUT4 vesicle arrival at the cell periphery and its subsequent tethering, docking, and fusion with the plasma membrane. The molecular machinery involved in GLUT...

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Autors principals: Boguslavsky, Shlomit, Chiu, Tim, Foley, Kevin P., Osorio-Fuentealba, Cesar, Antonescu, Costin N., Bayer, K. Ulrich, Bilan, Philip J., Klip, Amira
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469521/
https://ncbi.nlm.nih.gov/pubmed/22918957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-04-0263
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