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APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing
FZR1 is an anaphase-promoting complex (APC) activator best known for its role in the mitotic cell cycle at M-phase exit, in G1, and in maintaining genome integrity. Previous studies also established that it prevents meiotic resumption, equivalent to the G2/M transition. Here we report that mouse ooc...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3469513/ https://ncbi.nlm.nih.gov/pubmed/22918942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-05-0352 |
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