γ-Secretase inhibitors repress thymocyte development
A major therapeutic target in the search for a cure to the devastating Alzheimer's disease is γ-secretase. This activity resides in a multiprotein enzyme complex responsible for the generation of Aβ42 peptides, precipitates of which are thought to cause the disease. γ-Secretase is also a critical co...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11416218/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.131202798 |
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