Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia

BACKGROUND: Severe malarial anaemia (SMA) is a major life-threatening complication of paediatric malaria. Protracted production of pro-inflammatory cytokines promoting erythrophagocytosis and depressing erythropoiesis is thought to play an important role in SMA, which is characterized by a high TNF/...

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Hauptverfasser: Boeuf, Philippe S, Loizon, Séverine, Awandare, Gordon A, Tetteh, John KA, Addae, Michael M, Adjei, George O, Goka, Bamenla, AL Kurtzhals, Jørgen, Puijalon, Odile, Hviid, Lars, Akanmori, Bartholomew D, Behr, Charlotte
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469355/
https://ncbi.nlm.nih.gov/pubmed/22853732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-253
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