Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia

BACKGROUND: Severe malarial anaemia (SMA) is a major life-threatening complication of paediatric malaria. Protracted production of pro-inflammatory cytokines promoting erythrophagocytosis and depressing erythropoiesis is thought to play an important role in SMA, which is characterized by a high TNF/...

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Main Authors: Boeuf, Philippe S, Loizon, Séverine, Awandare, Gordon A, Tetteh, John KA, Addae, Michael M, Adjei, George O, Goka, Bamenla, AL Kurtzhals, Jørgen, Puijalon, Odile, Hviid, Lars, Akanmori, Bartholomew D, Behr, Charlotte
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469355/
https://ncbi.nlm.nih.gov/pubmed/22853732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-253
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