Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia

BACKGROUND: Severe malarial anaemia (SMA) is a major life-threatening complication of paediatric malaria. Protracted production of pro-inflammatory cytokines promoting erythrophagocytosis and depressing erythropoiesis is thought to play an important role in SMA, which is characterized by a high TNF/...

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Detalhes bibliográficos
Main Authors: Boeuf, Philippe S, Loizon, Séverine, Awandare, Gordon A, Tetteh, John KA, Addae, Michael M, Adjei, George O, Goka, Bamenla, AL Kurtzhals, Jørgen, Puijalon, Odile, Hviid, Lars, Akanmori, Bartholomew D, Behr, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469355/
https://ncbi.nlm.nih.gov/pubmed/22853732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-253
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