Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia

BACKGROUND: Severe malarial anaemia (SMA) is a major life-threatening complication of paediatric malaria. Protracted production of pro-inflammatory cytokines promoting erythrophagocytosis and depressing erythropoiesis is thought to play an important role in SMA, which is characterized by a high TNF/...

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Autors principals: Boeuf, Philippe S, Loizon, Séverine, Awandare, Gordon A, Tetteh, John KA, Addae, Michael M, Adjei, George O, Goka, Bamenla, AL Kurtzhals, Jørgen, Puijalon, Odile, Hviid, Lars, Akanmori, Bartholomew D, Behr, Charlotte
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469355/
https://ncbi.nlm.nih.gov/pubmed/22853732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-253
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