Identification of biochemical pathways for the metabolism of oxidized low-density lipoprotein derived aldehyde-4-hydroxy trans-2-nonenal in vascular smooth muscle cells

Oxidation of low-density lipoproteins (LDL) generates high concentrations of unsaturated aldehydes, such as 4-hydroxy trans-2-nonenal (HNE). These aldehydes are mitogenic to vascular smooth muscle cells and sustain a vascular inflammation. Nevertheless, the processes that mediate and regulate the va...

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Bibliografiske detaljer
Main Authors: Srivastava, Sanjay, Conklin, Daniel J, Liu, Si-Qi, Prakash, Nidhi, Boor, Paul J, Srivastava, Satish K, Bhatnagar, Aruni
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469324/
https://ncbi.nlm.nih.gov/pubmed/11583712
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