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Lipid Peroxidation Product 4-Hydroxy-trans-2-nonenal Causes Endothelial Activation by Inducing Endoplasmic Reticulum Stress

Lipid peroxidation products, such as 4-hydroxy-trans-2-nonenal (HNE), cause endothelial activation, and they increase the adhesion of the endothelium to circulating leukocytes. Nevertheless, the mechanisms underlying these effects remain unclear. We observed that in HNE-treated human umbilical vein...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vladykovskaya, Elena, Sithu, Srinivas D., Haberzettl, Petra, Wickramasinghe, Nalinie S., Merchant, Michael L., Hill, Bradford G., McCracken, James, Agarwal, Abhinav, Dougherty, Susan, Gordon, Sharon A., Schuschke, Dale A., Barski, Oleg A., O'Toole, Timothy, D'Souza, Stanley E., Bhatnagar, Aruni, Srivastava, Sanjay
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322871/
https://ncbi.nlm.nih.gov/pubmed/22228760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.320416
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