Lipid Peroxidation Product 4-Hydroxy-trans-2-nonenal Causes Endothelial Activation by Inducing Endoplasmic Reticulum Stress

Lipid peroxidation products, such as 4-hydroxy-trans-2-nonenal (HNE), cause endothelial activation, and they increase the adhesion of the endothelium to circulating leukocytes. Nevertheless, the mechanisms underlying these effects remain unclear. We observed that in HNE-treated human umbilical vein...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Vladykovskaya, Elena, Sithu, Srinivas D., Haberzettl, Petra, Wickramasinghe, Nalinie S., Merchant, Michael L., Hill, Bradford G., McCracken, James, Agarwal, Abhinav, Dougherty, Susan, Gordon, Sharon A., Schuschke, Dale A., Barski, Oleg A., O'Toole, Timothy, D'Souza, Stanley E., Bhatnagar, Aruni, Srivastava, Sanjay
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2012
الموضوعات:
Molecular Bases of Disease
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322871/
https://ncbi.nlm.nih.gov/pubmed/22228760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.320416
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