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Polyvalent Side Chain Peptide – Synthetic Polymer Conjugates as HIV-1 Entry Inhibitors

This report describes the synthesis and properties of a series of polyvalent side chain peptide – synthetic polymer conjugates designed to block the CD4 binding site on gp120 and inhibit HIV-1 entry into a host cell. The peptide sequences in the conjugates are based on the CDR H3 region of the neutr...

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Autors principals: Danial, Maarten, Root, Michael J., Klok, Harm-Anton
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468941/
https://ncbi.nlm.nih.gov/pubmed/22455441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm300150q
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