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Polyvalent Side Chain Peptide – Synthetic Polymer Conjugates as HIV-1 Entry Inhibitors
This report describes the synthesis and properties of a series of polyvalent side chain peptide – synthetic polymer conjugates designed to block the CD4 binding site on gp120 and inhibit HIV-1 entry into a host cell. The peptide sequences in the conjugates are based on the CDR H3 region of the neutr...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468941/ https://ncbi.nlm.nih.gov/pubmed/22455441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm300150q |
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