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Ogg1 null mice exhibit age-associated loss of the nigrostriatal pathway and increased sensitivity to MPTP
Cumulative damage to cellular macromolecules via oxidative stress is a hallmark of aging and neurodegenerative disease. Whether such damage is a cause or a subsequent effect of neurodegeneration is still unknown. This paper describes the development of an age-associated mild parkinsonian model in mi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468700/ https://ncbi.nlm.nih.gov/pubmed/22743193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2012.06.013 |
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