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The Effects of Amino Acid Composition of Glutamine-Rich Domains on Amyloid Formation and Fragmentation
Fragmentation of amyloid polymers by the chaperone Hsp104 allows them to propagate as prions in yeast. The factors which determine the frequency of fragmentation are unclear, though it is often presumed to depend on the physical strength of prion polymers. Proteins with long polyglutamine stretches...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468588/ https://ncbi.nlm.nih.gov/pubmed/23071575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046458 |
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