HCl-induced and ATP-dependent upregulation of TRPV1 receptor expression and cytokine production by human esophageal epithelial cells

The pathogenesis of gastroesophageal reflux disease (GERD) remains elusive, but recent evidence suggests that early secretion of inflammatory cytokines and chemokines by the mucosa leads to influx of immune cells followed by tissue damage. We previously showed that exposure of esophageal mucosa to H...

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Bibliografiske detaljer
Main Authors: Ma, Jie, Altomare, Annamaria, Guarino, Michele, Cicala, Michele, Rieder, Florian, Fiocchi, Claudio, Li, Dan, Cao, Weibiao, Behar, Jose, Biancani, Piero, Harnett, Karen M.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Mucosal Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468560/
https://ncbi.nlm.nih.gov/pubmed/22790593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00097.2012
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