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HCl-induced and ATP-dependent upregulation of TRPV1 receptor expression and cytokine production by human esophageal epithelial cells

The pathogenesis of gastroesophageal reflux disease (GERD) remains elusive, but recent evidence suggests that early secretion of inflammatory cytokines and chemokines by the mucosa leads to influx of immune cells followed by tissue damage. We previously showed that exposure of esophageal mucosa to H...

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Main Authors: Ma, Jie, Altomare, Annamaria, Guarino, Michele, Cicala, Michele, Rieder, Florian, Fiocchi, Claudio, Li, Dan, Cao, Weibiao, Behar, Jose, Biancani, Piero, Harnett, Karen M.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468560/
https://ncbi.nlm.nih.gov/pubmed/22790593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00097.2012
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