HCl-induced inflammatory mediators in esophageal mucosa increase migration and production of H(2)O(2) by peripheral blood leukocytes

Exposure of esophageal mucosa to hydrochloric acid (HCl) is a crucial factor in the pathogenesis of reflux disease. We examined supernatant of HCl-exposed rabbit mucosa for inflammatory mediators enhancing migration of leukocytes and production of H(2)O(2) as an indicator of leukocyte activation. A...

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Autors principals: Ma, Jie, Altomare, Annamaria, de la Monte, Suzanne, Tong, Ming, Rieder, Florian, Fiocchi, Claudio, Behar, Jose, Shindou, Hideo, Biancani, Piero, Harnett, Karen M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
Matèries:
Inflammation/Immunity/Mediators
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950690/
https://ncbi.nlm.nih.gov/pubmed/20616304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00160.2010
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