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Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia
Antral gastrin is the hormone known to stimulate acid secretion and proliferation of the gastric corpus epithelium. Patients with mutations in the multiple endocrine neoplasia type 1 (MEN1) locus, which encodes the protein menin, develop pituitary hyperplasia, insulinomas, and gastrinomas in the duo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468536/ https://ncbi.nlm.nih.gov/pubmed/22766853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00109.2012 |
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