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Does the ΔF508-CFTR mutation induce a proinflammatory response in human airway epithelial cells?

In the clinical setting, mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene enhance the inflammatory response in the lung to Pseudomonas aeruginosa (P. aeruginosa) infection. However, studies on human airway epithelial cells in vitro have produced conflicting results re...

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Bibliografiske detaljer
Main Authors: Hampton, Thomas H., Ballok, Alicia E., Bomberger, Jennifer M., Rutkowski, Melanie R., Barnaby, Roxanna, Coutermarsh, Bonita, Conejo-Garcia, José R., O'Toole, George A., Stanton, Bruce A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468482/
https://ncbi.nlm.nih.gov/pubmed/22821996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00226.2011
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