Soluble guanylyl cyclase is a target of angiotensin II-induced nitrosative stress in a hypertensive rat model

Nitric oxide (NO) by activating soluble guanylyl cyclase (sGC) is involved in vascular homeostasis via induction of smooth muscle relaxation. In cardiovascular diseases (CVDs), endothelial dysfunction with altered vascular reactivity is mostly attributed to decreased NO bioavailability via oxidative...

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Bibliographic Details
Main Authors: Crassous, Pierre-Antoine, Couloubaly, Samba, Huang, Can, Zhou, Zongmin, Baskaran, Padmamalini, Kim, David D., Papapetropoulos, Andreas, Fioramonti, Xavier, Durán, Walter N., Beuve, Annie
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Integrative Cardiovascular Physiology and Pathophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468472/
https://ncbi.nlm.nih.gov/pubmed/22730391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00138.2012
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