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Protein disulfide isomerase interacts with soluble guanylyl cyclase via a redox-based mechanism and modulates its activity
Nitric oxide (NO) binds to the receptor, soluble guanylyl cyclase (sGC), stimulating cGMP production. The NO-sGC-cGMP pathway is a key component in the cardiovascular system. Discrepancies in sGC activation and deactivation in vitro vs. in vivo have led to a search for endogenous factors that regula...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992929/ https://ncbi.nlm.nih.gov/pubmed/23477350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130298 |
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