Soluble guanylyl cyclase is a target of angiotensin II-induced nitrosative stress in a hypertensive rat model

Nitric oxide (NO) by activating soluble guanylyl cyclase (sGC) is involved in vascular homeostasis via induction of smooth muscle relaxation. In cardiovascular diseases (CVDs), endothelial dysfunction with altered vascular reactivity is mostly attributed to decreased NO bioavailability via oxidative...

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Main Authors: Crassous, Pierre-Antoine, Couloubaly, Samba, Huang, Can, Zhou, Zongmin, Baskaran, Padmamalini, Kim, David D., Papapetropoulos, Andreas, Fioramonti, Xavier, Durán, Walter N., Beuve, Annie
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2012
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468472/
https://ncbi.nlm.nih.gov/pubmed/22730391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00138.2012
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