Mechanism of the inhibition of mutagenicity of a benzo[a]pyrene 7,8-diol 9,10-epoxide by riboflavin 5'-phosphate.

Riboflavin 5'-phosphate (flavin mononucleotide; FMN) inhibits the mutagenicity of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (B[a]P diol epoxide), the only known ultimate carcinogenic metabolite of benzo[a]pyrene. Coincubation of 10, 25, and 50 nmol of...

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izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Wood, A W, Sayer, J M, Newmark, H L, Yagi, H, Michaud, D P, Jerina, D M, Conney, A H
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1982
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6813854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.17.5122
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