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Quantifying uniformity of mapped reads

Summary: We describe a tool for quantifying the uniformity of mapped reads in high-throughput sequencing experiments. Our statistic directly measures the uniformity of both read position and fragment length, and we explain how to compute a P-value that can be used to quantify biases arising from exp...

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Detalhes bibliográficos
Main Authors: Hower, Valerie, Starfield, Richard, Roberts, Adam, Pachter, Lior
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467739/
https://ncbi.nlm.nih.gov/pubmed/22815359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts451
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