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Association mapping from sequencing reads using k-mers

Genome wide association studies (GWAS) rely on microarrays, or more recently mapping of sequencing reads, to genotype individuals. The reliance on prior sequencing of a reference genome limits the scope of association studies, and also precludes mapping associations outside of the reference. We pres...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Rahman, Atif, Hallgrímsdóttir, Ingileif, Eisen, Michael, Pachter, Lior
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044908/
https://ncbi.nlm.nih.gov/pubmed/29897334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32920
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