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IgG2a monoclonal antibodies inhibit human tumor growth through interaction with effector cells.

Monoclonal antibodies of IgG2a isotype specifically inhibited growth of human tumors in nude mice. Twenty-three monoclonal antibodies of other isotypes showed no tumoricidal reactivity. Complement depletion of nude mice had no effect on tumor suppression by monoclonal antibody. The role of T and kil...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Herlyn, D, Koprowski, H
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1982
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346757/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6289317/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.15.4761
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